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    [ Data Generation Services ]

    Four platforms.
    Countless use cases.
    One data generation partner.

    Each service is built for AI-readiness from day one, automated, reproducible, and delivered in ML-ready formats. Select a service to explore the assay menu and download the full overview deck.

    01

    Antibody Developability

    Biophysical characterization for drug-like antibodies.

    AbDev

    Screen over 2,400 antibody designs in parallel across 10+ biophysical assays. Our PROPHET-Ab platform generates AI-ready data with run-to-run consistency validated against published literature, from pilot screens to full training sets. Compatible with IgG, VHH, Fc-fusions, Fab, scFv, and multi-specifics.

    [ Assay Menu ]

    Aggregation (SEC)Thermostability (nanoDSF)Functional AssessmentsHydrophobicity (HIC)Colloidal Stability (SMAC)Polyreactivity (CHO/Ova)Self-Association (AC-SINS)Self-Interaction (DLS-kD)Heparin Binding (HAC)FcRn Binding (BLI)Fragmentation (CE-SDS)Target Binding (BLI)TiterFormulation Screen (FaST)Binding

    [ Use Cases ]

    →Arrayed AbDev screens — 1,280 antibodies + 7 assays in 6–7 weeks
    →ML training datasets for developability prediction models
    →Lead optimization — de-risk pipeline liabilities early
    →Formulation buffer screening and stress testing
    →Lab-in-the-loop campaigns with generative design partners
    →Antibody Developability Consortium — founding members AbbVie, argenx, Lundbeck & Takeda; 10,000-antibody federated dataset via Apheris

    [ AI/ML ]

    Aggregation, thermostability & stability predictors

    Expression yield predictors

    Developability-guided sequence generation via discrete diffusion + SVDD

    Multi-parameter optimization across biophysical axes

    PDF

    Antibody Developability — Service Overview

    Full assay specs, validation data, timelines, and case studies

    Your information is kept confidential and used only to send you relevant updates from Ginkgo Datapoints.

    02

    Perturbation Response Profiling

    HT-transcriptomics and morphological responses to genetic or chemical treatment.

    Omics

    Accelerate target ID to hit-to-lead with industrialized Cell Painting and DRUG-seq. Multi-dimensional profiling at library scale across primary human cell types—from cell culture to AI/ML-ready output. Turbocharge screening cascades, power virtual cell models, and de-risk siRNA/ASO programs.

    [ Assay Menu ]

    DRUG-seqCell PaintingHigh Content ImagingCRISPR KOsiRNA / ASO / oligoChemical perturbationPrimary Human CellsiPSC-derived ModelsDose-ResponseOrganoidsImmune Cell ProfilingHepatocyte Toxicity

    [ Use Cases ]

    →Full library screens: 20K+ compounds with transcriptomic and morphological readouts
    →Arrayed whole-genome knockouts with weekly data delivery
    →MoA deconvolution, classify compounds by pathway activation
    →Toxicity screening in HepaRG, organoid, and primary cells
    →siRNA on/off-target screening at scale

    [ AI/ML ]

    MoA classifiers using multimodal data

    Gene expression and pathway activation predictors

    Unsupervised compound profiling

    Lab-in-the-loop active learning integration

    Virtual cell pharmacology models (VCPI)

    PDF

    Perturbation Response Profiling — Service Overview

    Full assay specs, validation data, timelines, and case studies

    Your information is kept confidential and used only to send you relevant updates from Ginkgo Datapoints.

    03

    Specialized HTS

    Tailored discovery assays to identify and validate hits, leads, and targets.

    HTS

    High-throughput screening built around your target and biology. From neurodegenerative iPSC models to combinatorial drug screens, we configure the right readouts for your question. Our specialized HTS capability operates as an extension of your R&D team, rapidly developing and validating custom assays so you can focus on the results.

    [ Assay Menu ]

    Phenotypic ScreeningTarget EngagementCell-Based FunctionaliPSC-derived ModelsPrimary Immune CellsCombinatorial TreatmentsCustom Assay DevelopmentNeurodegenerative ModelsReporter Gene AssaysDose-Response Profiling

    [ Use Cases ]

    →Phenotypic hit identification across large compound libraries
    →Target engagement validation in physiologically relevant cell models
    →Protein-protein interaction profiling using nanoBRET and proximity-based assays
    →Complex disease modeling, iPSC neurons, immune cell panels
    →Custom assay development for novel targets and readouts

    [ AI/ML ]

    Multi-modal feature extractors

    Unsupervised compound profiling

    Active learning for iterative hit ID

    Lead optimization ML integration

    PDF

    Specialized HTS — Service Overview

    Covered in the Perturbation Response Profiling deck. One deck, both services.

    ↑ Download above

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    04

    Small Molecule ADME

    ADMET testing at lead or library scale — now available as ADME-One™ with Tangible Scientific & Inductive Bio.

    ADME

    ADME-One™ is our integrated Tier 1 ADME offering: all five core assays generated end-to-end in Ginkgo's automated Boston lab, paired with Inductive Bio's Compass platform for AI-driven human PK projection and Tangible Scientific compound management — a single US-based workflow with rapid results at pricing that beats offshore alternatives. Individual à la carte assays remain available for teams who want to mix and match, with structured ML-ready data returns and no data locked in PDFs.

    [ Assay Menu ]

    Microsomal Stability (CLint / T½)Kinetic SolubilityP450 Inhibition — CYP1A2P450 Inhibition — CYP3A4P450 Inhibition — CYP2C9P450 Inhibition — CYP2C19P450 Inhibition — CYP2D6MDCK-MDR1 Permeability (Papp)Plasma Protein Binding (Fu)Mouse microsomesRat microsomesDog microsomesHuman microsomes

    [ Use Cases ]

    →ADME-One™ integrated workflow — Tier 1 panel + AI human PK projection + compound management in a single order
    →API-based ordering through Tangible Scientific
    →Library-scale ADME for ML training dataset generation
    →Lab-in-the-loop — integrate with Inductive Bio's Compass for iterative ADMET optimization
    →Multi-species profiling for cross-species PK prediction
    →Portfolio triage — rapid rank-ordering across compound sets

    [ AI/ML ]

    ADME/Tox predictors

    Solubility & permeability models

    Drug-likeness scoring

    Cross-species PK prediction

    Inductive Bio Compass integration

    PDF

    Small Molecule ADME — Service Overview

    Full assay specs, validation data, timelines, and case studies

    Your information is kept confidential and used only to send you relevant updates from Ginkgo Datapoints.

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