01 · Flexible
À la carte assays
Pick the assays and species you need.
Small Molecule ADME
Automated ADME/ADMET testing from single compounds to full libraries, run in Ginkgo’s Boston lab.
Every assay runs end-to-end on our robotic platform, and every result comes back as structured, ML-ready data, never locked in PDFs. Order individual assays, build a custom panel, generate a library-scale training set, or choose our integrated ADME-One™ package.
[ Three ways to work with us ]
02 · Scale
Library-scale ADME
Profile whole libraries to build ML training sets.
03 · Integrated package
ADME-One™
Tier 1 panel + AI PK projection + compound management.
Our Tier 1 core panel
Metabolic stability
How quickly is it broken down?
Microsomal stability
CLint · T½
Profile metabolic turnover in human, mouse, rat, or dog microsomes.
Permeability
Can it cross a cell barrier?
MDCK-MDR1
Papp
Measure permeability using the MDCK-MDR1 assay.
Solubility
How much stays in solution?
Kinetic solubility
Solubility
Measure kinetic solubility to identify poorly soluble compounds.
Protein binding
How much remains unbound?
Plasma protein binding
Fu
Measure the unbound fraction in plasma.
CYP inhibition
Does it inhibit drug metabolism?
Five CYP isoforms
IC50
CYP1A2, CYP3A4, CYP2C9, CYP2C19, and CYP2D6.
ADME-One™ · Tier 1 ADME, done early
One connected workflow: compound management, Tier 1 assays and AI PK projection.
$199/ compound
- 01
Submit compounds
Compound management & logistics
Complimentary, or use your existing provider.
- 02
Measure ADME
Five assay core panel
Individual assays and add-ons also available.
- 03
Project human PK
AI contextualization of measured results
You retain ownership of your data. No additional modeling required.
[ Ginkgo lab automation ]
Built for scale. Priced for your entire hit series.
High-throughput automation scales our assays and lowers the cost. That’s how we make comprehensive ADME accessible at industry leading value.
ADME — Service Overview
Assay specifications, validation & project details