Biophysical Characterization Data

Antibody Developability

We generate biophysical antibody characterization developability datasets for you to use in AI model training and validation. Our world-class wet lab infrastructure offers you the scale and breadth you need to unlock AI for antibody developability.

How It Works

We take your antibody sequences as input, perform wet lab workflows in high-throughput, and return AI-ready datasets as output.

We synthesize, express, and purify the antibodies, perform broad biophysical characterization, analyze and integrate the data, and return an AI-ready dataset to you.

Select from a range of developability assays

Designed with your needs in mind

01

Breadth & Scale

Screen 2,400+ antibody sequences in parallel across 10+ assays targeting key biophysical properties, powered by our >$1 billion Boston wet lab infrastructure.

02

AI-ready Data & AI Expertise

Generate AI-ready data through our standardized screening platform, powered by our team of AI and biophysics experts and proprietary software.

03

Simple & Easy Terms

Fee-for-service only: no royalties, no milestones. And you own the data, always. Our version of an easy button.

Sample Dataset


Interact with a sample dataset

This dataset provides an example of the antibody developability data we can generate. We produced and tested 20 IgG antibodies previously characterized in Jain et al (PNAS 2017). See below for more details about how this data was generated and terms of use.

How was the data generated?

DNA sequences for each IgG were synthesized and transfected into HEK293F cells. Expressed IgGs were purified with protein-A-based resins then characterized with the following developability assays: thermostablity by nanoDSF, aggregation by SE-HPLC, colloidal stability by SMA-HPLC, Hydrophobicity by HI-HPLC, Self association by AC-SINS. The downloadable dataset includes assay parameters and data output for each of the above assays. There is also a readme file with more details on the assays and descriptions of each of the fields in the dataset.

Terms of use

By clicking ‘Download’ and accessing the dataset included therein (the “data”) you acknowledge and agree that: (1) the data is solely owned by Ginkgo Bioworks, Inc. and/or its affiliates and/or representatives (collectively, “Ginkgo”) and you are not granted any license thereto except solely as necessary for the limited purpose of determining whether to pursue a data generation agreement with Ginkgo (“the Purpose”) and for no other purpose; (2) you may not copy, modify, sell, lease, or distribute the data (except as necessary for the Purpose); (3) in no event will Ginkgo be liable to you or any third party for any consequential, special, indirect, incidental, punitive or exemplary damages, costs, expenses or losses (including lost profits) (collectively, “damages”), regardless of the form of action or the basis for such claim or liability arising in any way from your access to or use of the data; and (4) Ginkgo does not make any representations, warranties or guarantees of any kind with respect to the data, either express or implied, including any warranty of quality, merchantability, or fitness for a particular use or purpose or any warranty as to non-infringement of any intellectual property rights of third parties.

Tell us what data you need. We’ll generate a large antibody developability dataset to power your AI model.

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